Archive for Publications

VERTICALLY INTEGRATED TRANSLATIONAL STUDIES OF PDX1 AS A THERAPEUTIC TARGET FOR PANCREATIC CANCER VIA A NOVEL BIFUNCTIONAL RNAI PLATFORM

Vertically Integrated Translational Studies of PDX1 as a Therapeutic Target for Pancreatic Cancer via a Novel Bifunctional RNAi Platform.

PHARMACOKINETIC STUDY OF OMACETAXINE MEPESUCCINATE ADMINISTERED SUBCUTANEOUSLY TO PATIENTS WITH ADVANCED SOLID AND HEMATOLOGIC TUMORS

Pharmacokinetic Study of Omacetaxine Mepesuccinate Administered Subcutaneously to Patients with Advanced Solid and Hematologic Tumors.

IMMUNE RESPONSE AND SURVIVAL OF REFRACTORY CANCER PATIENTS WHO RECEIVED TGF-Β2 ANTISENSE/GM-CSF GENE MODIFIED AUTOLOGOUS TUMOR CELL (TAG) VACCINE

Immune Response and Survival of Refractory Cancer Patients Who Received TGF-β2 Antisense/GM-CSF Gene Modified Autologous Tumor Cell (TAG) Vaccine.

VERTICALLY INTEGRATED TRANSLATIONAL STUDIES OF PDX1 AS A THERAPEUTIC TARGET FOR PANCREATIC CANCER VIA A NOVEL BIFUNCTIONAL RNAI PLATFORM

Phase 2 Trial of Erlotinib With or Without PF-3512676 (CPG 7909, a Toll-like Receptor 9 Agonist) in Patients With Advanced Recurrent EGFR-Positive Non-Small Cell Lung Cancer.

NOTCH1 ACTIVATION UP-REGULATES PANCREATIC AND DUODENAL HOMEOBOX-1

Notch1 Activation Up-Regulates Pancreatic and Duodenal Homeobox-1.

RNAI AND PERSONALIZED CANCER THERAPY

Rao DD, Wang Z, Senzer N, Nemunaitis J: RNAi and Personalized Cancer Therapy. Discovery Medicine 2013 Feb; 15(81):101-110.

PHASE 2 TRIAL OF ERLOTINIB WITH OR WITHOUT PF-3512676 (CPG 7909, A TOLL-LIKE RECEPTOR 9 AGONIST) IN PATIENTS WITH ADVANCED RECURRENT EGFR-POSITIVE NON-SMALL CELL LUNG CANCER.

Phase 2 Trial of Erlotinib With or Without PF-3512676 (CPG 7909, a Toll-like Receptor 9 Agonist) in Patients With Advanced Recurrent EGFR-Positive Non-Small Cell Lung Cancer.

A PHASE 1 TRIAL OF ORAL RIDAFOROLIMUS (AP23573; MK-8669) IN COMBINATION WITH BEVACIZUMAB FOR PATIENTS WITH ADVANCED CANCERS

A Phase 1 Trial of Oral Ridaforolimus (AP23573; MK-8669) in Combination With Bevacizumab for Patients With Advanced Cancers.

A FIRST-IN-HUMAN, PHASE 1, DOSE-ESCALATION STUDY OF DINACICLIB, A NOVEL CYCLIN-DEPENDENT KINASE INHIBITOR, ADMINISTERED WEEKLY IN SUBJECTS WITH ADVANCED MALIGNANCIE

A First-in-human, Phase 1, Dose-escalation Study of Dinaciclib, a Novel Cyclin-dependent Kinase Inhibitor, Administered Weekly in Subjects with Advanced Malignancies.

SURROGATE MEASURES OF ACTIVITY

Nemunaitis J: Cancer Targeting Vaccines: Surrogate Measures of Activity. Human Vaccines & Immunotherapeutics 2013 Jan;9(1):213-218.