A Phase 1/2 Study to Evaluate the Safety, Tolerability, and Efficacy of TROP2-Directed Antibody-Drug Conjugate LCB84, as a Single Agent and in Combination With an Anti-PD-1 Ab, in Patients With Advanced Solid Tumors
Mechanism of Action
LCB84 is an anti-TROP2 ADC
Purpose
- How much of the study agent can be given alone or in combination with Pembrolizumab with an acceptable level of side effects
- The effects of the study agent alone or in combination with Pembrolizumab (good and bad)
- How much of the study agent is absorbed into the blood and how fast it is removed
- If research tests can be used in the future to predict who will benefit from LCB84
- How the study agent is acting on your body
Location
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