A Phase 1, Open-Label, Multicenter Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer

MC #22-27

NCT #
NCT05519449
Condition(s)
Prostate Cancer
Molecular Target(s)
CD3, PSMA
Drug Classification(s)
Targeted Immunotherapy
Agents(s)
JANX007
Phase(s)
I

Mechanism of Action

JANX007 is a Tumor Activated T Cell Engager therapuetic targeting prostate-specific membrane antigen (PSMA) for the treatment of metastatic castration-resistant prostate cancer.

Purpose

  • How much of the study agent can be given with an acceptable level of side effects
  • The effects of the study agent (good and bad)
  • How much of the study agent is absorbed into the blood and how fast it is removed
  • How the level of certain molecules (biomarkers) in your blood changes over time while receiving the study agent

Location

MCD

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