A Phase 1 Study Evaluating the Safety, Tolerability, and Efficacy of BL-B01D1 in Subjects With Metastatic or Unresectable Non-Small Cell Lung Cancer and Other Solid Tumors

MC #23-17

NCT #
NCT05983432
Condition(s)
Lung Cancer (NSCLC), Solid Tumor
Molecular Target(s)
EGFR, HER3
Drug Classification(s)
Antibody Drug Conjugate, Bispecific Antibodies
Agents(s)
BL-B01D1
Phase(s)
I

Mechanism of Action

EGFR x HER3 bispecific antibody-drug conjugate

Purpose

  • How much of BL-B01D1 can be given with an acceptable level of side effects
  • The effects of BL-B01D1 (good and bad)
  • How much of BL-B01D1 is absorbed into the blood and how fast it is removed

Location

MCD

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