Phase 1/2 Study of PRO1184 in Patients With Locally Advanced and/or Metastatic Solid Tumors
NCT #
NCT05579366
Condition(s)
Breast Cancer, Endometrial Cancer, Lung Cancer (NSCLC), Mesothelioma, Ovarian/ Peritoneal/ Fallopian Tube Cancer
Molecular Target(s)
FRĪ±
Drug Classification(s)
Antibody Drug Conjugate
Agents(s)
PRO1184
Phase(s)
I/II
Mechanism of Action
PRO1184 is an antibody drug conjugate that is directed to folate molecules to bind to cells with folate receptor in order to deliver the attached cytotoxic payload molecules
Purpose
- How much of the study agent can be given with an acceptable level of side effects
- The effects of the study agent (good and bad)
- How much of the study agent is absorbed into the blood and how fast it is removed
- If research tests can be used in the future to predict who will benefit from PRO1184
- How the study agent is acting on your body
Location
MCD
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