First-in-human trial of the oral first-in-class Ubiquitin Specific Peptidase 1 (USP1) inhibitor RO7623066 (KSQ-4279), given as single agent and in combination with olaparib or carboplatin in patients with advanced solid tumors, enriched for deleterious homologous recombination repair (HRR) mutations
Wednesday, September 18, 2024